For a long time, researchers and medical professionals have had difficulty defining, quantifying, and treating cognitive tiredness; they have primarily relied on people’s self-reports of their level of exhaustion. But a new report in Nature sheds light on why our brain gets tired.

The Paris Brain Institute’s research director and cognitive neuroscientist, Mathias Pessiglione, was interested in learning more about the fatigued brain. “Why is this cognitive system prone to fatigue?” was his question.

In order to investigate the metabolic causes and effects of cognitive tiredness, scientists from several fields are now using cutting-edge experimental techniques and biological markers.

What exactly is cognitive fatigue?

Cognitive fatigue is a universal human experience, the mental exha

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