More than 250 people who were exposed to measles, including dozens of school-age children, are quarantining in South Carolina as the state wrestles to contain an outbreak that has sickened more than 110 people.

The outbreak comes during what has already been one of the worst years for the virus since it was declared eliminated in the United States more than two decades ago.

Cases have been centered in Spartanburg County, along the northern border of the state, and the virus appears to be widely spreading through the community: People have been exposed at a church, a health care building and several schools.

The outbreak, which started in October, shows no signs of slowing, likely because of the county’s “lower-than-hoped-for vaccination coverage,” Dr. Linda Bell, South Carolina’s state

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