One man has died and another has been seriously injured in a shooting outside a hotel in Sydney's inner-city.

Police were called to The Harold Hotel on Ross Street in Forest Lodge about 6:40pm, following reports of a public place shooting.

When officers arrived, they found two people had been shot multiple times by unknown people who fled in a car.

Paramedics treated the two men at the scene, but one could not be saved.

The other man was treated for gunshot wounds and was taken to hospital in a serious condition.

Detectives have cordoned off part of the street with police tape, as a manhunt for the gunmen continues.

Nearby resident Imogen said she heard about six "really loud bangs" but initially mistook them for fireworks.

"I saw some people running across the road, so away from wh

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