Data from several massive genetic databases have linked digestive disorders with Alzheimer’s disease (AD) and Parkinson’s disease (PD) and provided a window on the genetic and proteomic basis behind this.
The findings, in Science Advances , once more demonstrate the importance of the gut-brain axis, a complex and bidirectional communication network linking the gastrointestinal tract with the central nervous system.
The current study revealed how combining co-occurring disorders of the gut-brain axis with genetic and proteomic data can better predict the risk of neurodegenerative disease.
It showed that people with non-infective colitis, gastritis, and esophagitis had a higher rate of developing Alzheimer’s or Parkinson’s disease. This was also the case for those with functional inte