The Florida State Seminoles will host the No. 8 Alabama Crimson Tide in a Week 1 college football clash on Saturday. The Seminoles are coming off of a disastrous 2024 season that left them at the bottom of the ACC with a 2-10 overall record. Meanwhile, the Crimson Tide went 9-4 in head coach Kalen DeBoer's first season in Tuscaloosa.

Kickoff from Doak Campbell Stadium in Tallahassee is set for 3:30 p.m. ET. The Crimson Tide are 13.5-point favorites in the latest Alabama vs. Florida State odds from SportsLine consensus, while the over-under for total points scored is set at 48.5. Before making any Florida State vs. Alabama picks, make sure you check out the picks from the SportsLine projection model. New users at bet365 can get $200 in bonus bets instantly with the latest bet365

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