Key takeaways:

Being male or aged older than 40 years were consistently associated with poorer acute optic neuritis outcomes.

Better high-contrast visual acuity predicted better results in almost all outcomes.

Perspective from Alek Karthikeyan, OD, FAAO

Outcomes in acute optic neuritis tend to be worse at 6 months for men, patients who are older and those with poorer high-contrast visual acuity at baseline, according to an analysis published in Ophthalmology .

“Two avenues of interest recently have opened regarding the treatment of [optic neuritis]: First, data from small case series suggest a possible benefit of early [glucocorticosteroid] treatment, usually defined as administration within 48 hours of symptom onset,” Sebastian Küchlin, MD , of the University of Freiburg, Germ

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