Calls for the impeachment of Robert F. Kennedy and demands for his resignation escalated on Thursday following a contentious hearing with Senate lawmakers, with even conservative Bill Kristol stating, "I've seen enough."

Kennedy, the Health and Human Services Secretary, was criticized by senators over recent moves, including firing Centers for Disease Control and Prevention Director Susan Monarez, a Trump appointee, and firing the full panel of the vaccine advisory board. Democrats have accused him of putting the public in great danger over spreading misinformation and gutting evidence-based research over vaccines, Axios reports.

And now the number of GOP critics are growing as support for him wanes, with some indicating Kennedy could be a liability as Republicans head into the midterm elections.

Kristol, editor at-large of The Bulwark, who served as chief of staff for Vice President Dan Quayle during the George H.W. Bush administration, sounded off after the fiery exchange in Washington, D.C.

"I’ve seen enough. Impeach Robert F. Kennedy, Jr.," Kristol posted.

He isn't the only voice calling for action.

"Impeach that quack, @SenBillCassidy. He’s irredeemable. Every day you delay risks more dead Americans. How much blood do you want on your hands?" conservative commentator Sarah Rumpf posted on X.

"Impeach his deeply dishonest and unhealthy ass!" Nation writer Joan Walsh posted on X.

Others issued a similar directive and demanded impeachment also apply to U.S. Supreme Court judges following news Thursday that nearly a dozen currently serving federal judges criticized the U.S. Supreme Court from behind the cloak of anonymity.

In a report cited on background with NBC News, judges described a growing concern over the court's increasingly frequent habit of overturning lower court rulings involving President Donald Trump's policies with little or no explanation.

"Another reason that impeachment must be on the table for judges," conservative activist and commentator Tom Fitton of Judicial Watch posted on X.