For all of their struggles in 2024, the New York Giants played the Washington Commanders extremely tough.

New York went 0-2 with the two defeats coming by eight combined points, including its 21-18 loss at Northwest Stadium on Austin Seibert’s game-winning, 30-yard field goal at the gun in Week 2.

The Commanders enter the 2025 season as the NFC runners-up, and the Giants have not won in Week 1 since 2022. Still, funky things can happen in NFC East games, especially since the G-Men are 5-2 in their past seven trips to Landover, Md.

Here are the NFL Week 1 odds , how we expect the Giants-Commanders game to go down and how you can bet with the best NJ sportsbook promos .

Giants vs Commanders predictions and best bets

Giants +6: ( -110 at bet365 )

Under 45.5 points : ( -105 at

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