ELMONT, N.Y. — Ariana Grande and Lady Gaga set the tone at the MTV Video Music Awards on Sunday night with career-defining moments of their own.

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Ariana Grande and Lady Gaga set the stage at the MTV Video Music Awards on Sunday night with standout moments

Grande won Video of the Year and Best Pop, thanking her "therapists and gay people" in her speech

Gaga, the night's top nominee, won Artist of the Year and performed at Madison Square Garden

Mariah Carey received the Video Vanguard Award, delivering a medley of her hits, and the late Ozzy Osbourne was honored with a tribute performance

Grande scored two honors — video of the year and best pop video — and had the audience buzzing when she thanked her "therapists and gay people" during her acceptance speech.

Gaga

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