The Week 2 NFL schedule give us our first game with a double-digit NFL spread with Ravens vs. Browns (+12.5). That's despite eight of the last nine meetings between these teams being decided by 10 points or fewer, with Cleveland outright winning in two of the last three. If you prefer Week 2 NFL spreads that are much slimmer, there is no shortage of those, including the doubleheader on Monday night. Houston is a 2.5-point home favorite over Tampa at 7 p.m. ET on Monday, while the Chargers are 3.5-point road favorites versus Vegas at 10 p.m. ET.

Other anticipated matchups to make Week 2 NFL bets on include Cowboys vs. Giants (+5.5) and a Super Bowl rematch in Chiefs vs. Eagles (-1). The motivation factor will be at an all-time high for Kansas City as one shouldn't underestima

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