After PCI, DAPT may lower risk for ischemic events vs. monotherapy

Key takeaways:

P2Y12 monotherapy after PCI was not as protective from ischemic events vs. DAPT with aspirin.

Monotherapy did reduce bleeding risk.

Aspirin remains an important component of care early after PCI.

Early P2Y12 monotherapy after PCI for acute coronary syndrome was not noninferior compared with dual antiplatelet therapy with aspirin, but did reduce risk for bleeding events, a speaker reported.

The results of the multicenter, open-label, randomized NEO-MINDSET trial were presented at the European Society of Cardiology Congress and simultaneously published in The New England Journal of Medicine .

P2Y12 monotherapy after PCI was not as protective from ischemic events vs. DAPT with aspirin. Image: Adobe Stock

“ DAPT, aspirin plus a P2Y12 inhibitor , is standard for patie