Sometimes, fantasy football managers are challenged by circumstances that come up early in the season. But defenses are usually pretty level throughout . Here are the fantasy football defense/special teams rankings for Week 2 of the 2025 NFL season.

At the head of the list is the NFL’s best defense. The Denver Broncos are going to find themselves at the top of this list quite frequently this season. And even though they are playing a team that is coming off a good game, the Broncos are a super strong unit for Week 2.

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The Broncos meet a Colts team that scored on every possession in Week 1. The Colts might not score on any possession in Week 2. Ok, that’s a stretch, but it paints a picture of how much better the Colts’ opponent will be this week.

Against th

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