Thunder Dan's favorite RB matchups to exploit for Week 2 of 2025 - DFS running backs to target on DraftKings and FanDuel. These RB matchups are GPP and cash game opportunities.

Certain running backs are what we call "game-script independent" - meaning they are likely to get their 15 to 20 touches regardless of how the game unfolds. If their team is leading and running the football, they will see plenty of rushes, while they can still pile up touches as a pass-catcher if their team is playing from behind.

For those backs, the matchup matters a little less. But those types of running backs have become very rare in today's NFL, and so finding the best matchups where running backs can thrive becomes more and more important each week.

My goal in this weekly article will be to highlight the a

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