In this Healio video, Philip J. Mease, MD , director of rheumatology research at Providence Swedish Medical Center in Seattle, discusses recently developed definitions for difficult-to-treat and complex-to-manage psoriatic arthritis.

“What do we do about the patient who comes into our clinic who has now been on multiple different biologics?” Mease said about the results of the research project presented at the EULAR annual meeting.

Some patients fail to respond to PsA treatments such as TNF inhibitors, interleukin-1 7 inhibitors and IL-23 inhibitors, Mease said, and these groups of patients with difficult-to-treat disease lacked precise definitions. The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) has recently developed a set of definitions for diffic

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