The Colorado Buffaloes (1-2) return home to Boulder to take on the Wyoming Cowboys (2-1) on Saturday. The Buffs are looking to bounce back from a 36-20 loss against Houston in their Big 12 opener in Week 3. CU head coach Deion Sanders has yet to formally announce if Kaidon Salter or Ryan Staub will be the team's starting quarterback, though Salter is reportedly in line to get the start. Wyoming is also coming off a blowout loss after falling to Utah 31-6 in its last outing. Colorado leads the all-time series 24-2-1.

Kickoff is set for 10:15 p.m. ET at Folsom Field in Boulder. The Buffs are 11.5-point favorites in the latest Colorado vs. Wyoming odds, while the over/under for total points scored is 45.5. Before making any Wyoming vs. Colorado picks, be sure to see what SportsLine expe

See Full Page