Even though the San Francisco 49ers are 3-0, they continue to lose some of their key starters, and now star pass-rusher Nick Bosa will miss the rest of the 2025 campaign with a torn ACL injury. According to the breaking news, the 49ers will have to move on from Bosa for now, as the defensive end isn't going to return. The good news seems too temporary for San Francisco since they've been able to win football games without starter Brock Purdy last week. However, the biggest question for the 49ers this season is how long this can last before everything slowly falters when they lose.

Despite that, it's a huge blow for the 49ers' defensive scheme either way, as the five-time Pro Bowler has always been consistent and dominant in several moments. However, this could invite the idea of trading f

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