Joey Pollizze analyzes all 2025 fantasy football Week 4 defenses (DEF) -- streamers, sits/starts, and D/ST waiver wire pickups to add. His Week 4 rankings and tiers for all of the NFL defenses.

Welcome, RotoBallers, to our fantasy football defense streamers, starts, and tiered rankings for Week 4 of the 2025 season! Every week of the season, this article will contain the best and worst defensive options. Each defense will be ranked No. 1 through No. 32 until the end of the fantasy football season. This will be your go-to stop for all defensive rankings and streamers for the year.

Last week, defenses ranked inside my top-10 (first two tiers) averaged 11.1 fantasy points, and defenses ranked in Tier 1 averaged 10 fantasy points. So, we will try to replicate that success in this week's defe

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