Key Takeaways

A semaglutide pill is effective for weight loss

Patients lost 14% to 17% of body weight taking the daily pill

The pill could offer an alternative to weekly injections of GLP-1 drugs

WEDNESDAY, Sept. 24, 2025 (HealthDay News) — A pill form of the blockbuster weight-loss drug Ozempic can help overweight or obese folks shed excess pounds, a new clinical trial has concluded.

People who took a daily semaglutide pill lost nearly 14% of their body weight over 64 weeks, compared with just 2% of those given a placebo, researchers reported recently in The New England Journal of Medicine .

Semaglutide is the main ingredient in the GLP-1 drugs Ozempic and Wegovy.

“The 25-mg dose resulted in substantial weight loss with a safety profile consistent with that of the GLP-1 cla

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