New Orleans Saints pass rusher Chase Young will miss his fourth straight game with a calf injury as he was ruled out Friday ahead of Sunday’s game against the Buffalo Bills.

The team will also be without guard Dillon Radunz, who is out for the second straight game with a toe injury.

But for the first time this year, the Saints are expected to have their initially projected offensive line as Trevor Penning (toe) will make his season debut. Taliese Fuaga, who has been hobbled by a back and knee injury, is also good to go after being a full participant over the last two days.

Wide receiver Devaughn Vele (hip) was listed as questionable.

Young originally suffered the calf injury days before the team’s season opener against the Arizona Cardinals. The team’s pass rush has struggled without

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