Big Ten behemoths clash when the sixth-ranked Oregon Ducks meet the third-ranked Penn State Nittany Lions on Saturday night. Oregon is coming off a 41-7 win over Oregon State in Week 4, while Penn State downed Villanova 52-6 on Sept. 13. The Ducks (4-0, 1-0 Big Ten), who won the conference regular-season title a year ago, are 6-0 on the road since the beginning of 2024. The Nittany Lions (3-0, 0-0 Big Ten), who tied for second in the conference at 8-1 and were 13-3 overall last season, are 10-1 on their home field since the start of 2024.

Kickoff from Beaver Stadium in University Park, Pa., is at 7:30 p.m. ET. Penn State leads the all-time series 3-2, but Oregon earned a 45-37 win in last year's Big Ten Championship Game. The Nittany Lions are 3.5-point favorites in the latest Penn St

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