A Seattle scientist, Mary E. Brunkow, was named among three Nobel Prize winners Monday for their advancements and discoveries related to the human immune system.

Brunkow, Fred Ramsdell, and Dr. Shimon Sakaguchi won the Nobel Prize in Physiology or Medicine, the first of many 2025 Nobel Prize announcements made at the Karolinska Institute in Stockholm, Sweden, according to The Associated Press .

“Their discoveries have been decisive for our understanding of how the immune system functions and why we do not all develop serious autoimmune diseases,” said Olle Kämpe, Chair of the Nobel Prize Committee.

Brunkow, 64, is a senior program manager at the Institute for Systems Biology in Seattle. Ramsdell, 64, is a scientific adviser for Sonoma Biotherapeutics in San Francisco. Sakaguchi, 74,

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