Two teenagers charged over the stabbing deaths of two children have refused to come to court for a compulsory DNA procedure, with prosecutors searching for a way to force them to attend.

The boys - aged 16 and 15 - were due to face a children's court on Friday after being charged with murder over the deaths of Chol Achiek, 12, and 15-year-old Dau Akueng.

They were allegedly set upon by a group of males at Cobblebank, in Melbourne's outer northwest, on September 6 while walking home from a basketball match.

Prosecutors have applied for the two accused, who are among eight males charged over the murders, to undergo a compulsory procedure to obtain their DNA.

But the boys refused to get on the bus to court on Friday morning, a youth justice custodial operations manager told the court.

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