The Week 6 NFL schedule has a bit of everything with another London game, the biggest NFL spread of the season, a potential Super Bowl preview on Sunday night and a two-game slate on Monday. Packers vs. Browns has Green Bay as 14-point favorites, per the Week 6 NFL odds, making the Pack the biggest favorite, thus far, of the 2025 NFL season. Meanwhile, SNF will have one of the slimmest NFL lines with Chiefs vs. Lions (+2.5), which is a matchup many would like to see again come February. Then on MNF, there are identical 4.5-point spreads with Buffalo favored versus Atlanta, as well as Washington favorites against Chicago.

Those are just a handful of the 15 games you can make Week 6 NFL bets, prop predictions or create an NFL parlay on. Having quality NFL betting advice is almost a must wit

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