The Tampa Bay Buccaneers (4-1) will host the San Francisco 49ers (4-1) in an NFL Week 6 NFC showdown on Paramount+ . Baker Mayfield and the Bucs got back into the win column in Week 5 with a 38-35 win against the Seattle Seahawks. They will host a 49ers team that got a couple of days extra rest after defeating the Los Angeles Rams 26-23 in overtime on Thursday Night Football. The 49ers will not have Brock Purdy (toe) available on Sunday, leaving Mac Jones in line for his fourth appearance. The Buccaneers will be without wide receivers Mike Evans (hamstring) and Chris Godwin (leg), as well as running back Bucky Irving (foot/shoulder) on Sunday.

Kickoff from Raymond James Stadium is set for 4:25 p.m. ET on CBS and Paramount+. Tampa Bay is a 3.5-point favorite in the latest 49ers vs. B

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