At least three people are believed to have been killed after a UPS plane crashed shortly after takeoff near the Louisville International Airport, Kentucky Gov. Andy Beshear said Tuesday night.

The number of fatalities is expected to increase, the governor said during a news conference. At least 11 injuries, some of which are significant, have been reported, he said.

Beshear said there was not hazardous cargo onboard the plane that would create environmental issues around the crash site, but urged residents to follow any shelter-in-place orders.

The Louisville Metro Police Department described the scene as active with "fire and debris," warning residents to stay away from Fern Valley and Grade Lane, an intersection located on the south side of the airport, which serves as the hub of UPS.

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