As the fantasy football season barrels into Week 10, wide receivers continue to make or break lineups . Between injury shakeups, inconsistent quarterback play, and brutal bye weeks, fantasy managers have been forced to take bold swings on upside plays. With elite wideouts like CeeDee Lamb, Ja’Marr Chase, and Rashee Rice sitting out on their byes, Week 10 will test roster depth and matchup savvy more than ever.

The good news is that a few offenses are poised for bounce-backs. In the same breath, a handful of ascending receivers are entering favorable matchups. Of course, others face brutal defensive assignments that could lead to major letdowns.

Ahead of Week 10 of the 2025 NFL Season , it’s time to see which RBs to start and which ones to sit in your fantasy football team.

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