A UPS cargo plane has crashed and exploded in a massive fireball while taking off from the company's global aviation hub in Kentucky, killing at least seven people and injuring 11.

The plane crashed on Tuesday afternoon as it was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport.

Video showed flames on the plane's left wing and a trail of smoke.

The plane then lifted slightly off the ground before crashing and exploding in a huge fireball.

Video also revealed portions of a building's shredded roof next to the end of the runway.

Among the 11 who were hurt, some had "very significant" injuries, Kentucky Governor Andy Beshear said.

"Anybody who has seen the images, the video, knows how violent this crash is," he said.

Beshear said he did not kno

See Full Page