At least seven people have died and 11 left with 'very significant' injuries after a UPS plane crashed at Muhammad Ali International Airport in Kentucky shortly after takeoff

A huge fire has been raging in a US city this morning after a UPS cargo plane crashed and exploded during a disastrous takeoff.

Seven people have died and another 11 left with "very significant" injuries after the disaster at Muhammad Ali International Airport in Kentucky on Wednesday, with authorities fearing the death toll could rise further.

The plane crashed at about 5.15pm local time (10pm GMT) after its left wing caught fire, causing a huge fireball as it plummeted to the ground. The McDonnell Douglas MD-11 aircraft, made in 1991, was departing for Hawaii from the UPS Worldport facility in Louisville,

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