A UPS cargo plane crashed shortly after takeoff from Louisville Muhammad Ali International Airport on Tuesday evening, killing at least seven people and injuring several more, Kentucky Gov. Andy Beshear said.

According to the Federal Aviation Administration, UPS Flight 2976 went down around 5:15 p.m. local time after departing the airport. Beshear said two businesses were hit when the plane crashed, and two employees are missing.

"First responders are onsite and working hard to extinguish the fire and continue the investigation," Beshear said. "Air monitoring assets have been deployed, and we are working to keep the public informed and keep folks in the area safe."

The McDonnell Douglas MD-11 was headed to Daniel K. Inouye International Airport in Honolulu when it crashed. The cause rem

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