LATEST UPDATES: Investigation set to begin into deadly UPS plane crash in Louisville. Read Nov. 5 updates.

A UPS cargo plane, loaded with fuel and bound for Honolulu, crashed shortly past the runway of Louisville Muhammad Ali International Airport at around 5:15 p.m. Nov. 4, marking the deadliest plane crash in the history of UPS Airlines.

As of 10:15 p.m., officials reported at least seven deaths and 11 injured from the disaster, and said the death toll could still climb. Hundreds of fire personnel worked to battle the blaze, intensified by the plane's 220,000 pounds of jet fuel. The blast produced a towering plume of smoke, visible from miles away to rush-hour commuters.

Louisville Fire Chief Brian O'Neill described the crash as an "incredible, large-scale mass-casualty inciden

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