The Week 13 college football schedule coincides with that annual late-season SEC slate where many of the teams face Group of Five opponents. While 14 SEC teams are in action, just four games you can make Week 13 college football picks on are conference matchups. It's highlighted by Oklahoma vs. Missouri, a top-25 matchup that has OU as a 5.5-point favorite. There's just one other ranked contest, and it has Oregon as a 10.5-point favorite over USC, according to the latest Week 13 college football odds, in a matchup of two of the top three scoring teams since 2022.

Even with the lack of elite matchups, there are still several interesting games, many of them pitting bitter rivals versus one another. Among them are Tennessee vs. Florida (+3.5), UNC vs. Duke (-6.5), Texas vs. Arkansas (+8.5) a

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