Key Takeaways

Psychedelics may increase risk of mania

People treated in a hospital for hallucinogen use were six times more likely to be diagnosed with mania

They were also four times more likely to be diagnosed with bipolar disorder

WEDNESDAY, Dec. 3, 2025 (HealthDay News) — A bad psychedelic trip might have long-term consequences for a person’s mood, researchers say.

Folks who land in the hospital due to hallucinogens are six times more likely to be diagnosed with mania within a few years, according to results published Dec. 2 in the journal PLOS Medicine .

“Our study showed a strong association between hallucinogen use that requires care in the emergency room or hospital and future risk of mania and bipolar disorder,” lead researcher Dr. Daniel Myran , a family medicine, p

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