The Buffalo Bills are 5.5-point favorites in this week's matchup against the Cincinnati Bengals in Highmark Stadium. The game will kickoff at 1 pm and will air on FOX.

Here's some additional notes for this week's AFC clash:

Bills are 23-4 in December/January games since 2020 - the best record in the NFL during that span

Joe Burrow is 18-5 in December or later games including the postseason

Burrow is 2-0 including the postseason against the Bills

Bills are 13-2 (regular season + postseason) when James Cook has 100 rushing yards

Bengals are 3-0 in 2025 with Burrow as the starter

Mike Florio & Chris Simms | Pro Football Talk

The Bengals are a very different team with Joe Burrow back in action.

Florio's pick: Bengals 30, Bills 27.

Simms's pick: Bills 28, Bengals 24.

Pete Prisco |

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