For adults who have recovered from depression with the help of antidepressants , gradually reducing medication together with psychological support appears to be as effective as remaining on antidepressants for preventing relapse, according to a systematic review and network meta-analysis of 76 randomised controlled trials, published in The Lancet Psychiatry journal .

The authors emphasise that these findings do not suggest that antidepressants are unnecessary or that psychotherapy alone is adequate. Instead, they say the results underscore the importance of tailoring deprescribing to each individual, with a gradual individualised tapering of antidepressants alongside structured psychological support.

“Depression is often a recurring condition and without ongoing treatment as man

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