Houston Texans quarterback C.J. Stroud (7) throws a pass at GEHA Field at Arrowhead Stadium in Kansas City, Missouri.

The Arizona Cardinals (3-10) visit the Houston Texans (8-5) Sunday in Week 15. Kickoff from NRG Stadium in Houston, Texas, is scheduled for 1 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NFL odds around the Cardinals vs. Texans odds and make our expert NFL picks and predictions for the best bets.

The Cardinals are struggling and banged up. They have lost their last 5 games and are 1-10 since starting the season 2-0. They are coming off a 45-17 home loss to the LA Rams in Week 14, failing to cover as 9.5-point underdogs with the Over (48.5) cashing. It was their third game in their last 5 allowing over 40 points.

The Texans, on the other hand, have won 5 games in a row and are a game out of the AFC South lead. They are coming off a 20-10 win over the Kansas City Chiefs as 4.5-point road underdogs with the Under (42) cashing.

The Cardinals and Texans have split their 6 all-time meetings but the Texans beat the Cardinals 21-16 in Nov. 2023 as 5.5-point home favorites. The Under (47.5) cashed.

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Cardinals at Texans odds

Provided by BetMGM Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 3:53 p.m. ET.

  • Moneyline (ML): Cardinals +400 (bet $100 to win $400) | Texans -525 (bet $525 to win $100)
  • Against the spread (ATS): Cardinals +9.5 (-105) | Texans -9.5 (-115)
  • Over/Under (O/U): 42.5 (O: -110 | U: -110)

Cardinals at Texans key injuries

Cardinals

  • OL Evan Brown (personal) out
  • RB Emari Demercado (ankle) questionable
  • WR Marvin Harrison Jr. (heel) out
  • OL Paris Johnson Jr. (knee) out
  • CB Max Melton (heel) out
  • DL Walter Nolen (knee) questionable
  • S Dadrion Taylor-Demerson (ankle) out
  • S Jalen Thompson (hamstring) out
  • WR Xavier Weaver (hamstring) out

Texans

  • RB Nick Chubb (ribs) questionable
  • LB E.J. Speed (knee) questionable

Cardinals at Texans picks and predictions

Prediction

Texans 27, Cardinals 10

Moneyline

The Cardinals have scored only 17 offensive points in each of their last 3 games and are facing the league's top defense in both yards and points allowed. They will have 4 backups starting on the offensive line against Houston's dominant pass rush.

The Cardinals have allowed 27 or more points in 4 of their last 5 games and more than 40 in 3 of those games.

There is nothing about this game that suggests you can even consider betting the Cardinals. And at -525 odds, the Texans ML doesn't give you any value.

PASS.

Against the spread

The Cardinals are 1-4 ATS during their 5-game losing streak. The Texans are coming off a 10-point win over a Chiefs team that is much better than the Cardinals.

Cardinals QB Jacoby Brissett has passed for over 250 yards in all 8 of his starts, and that is the only thing going for the Cardinals this season at this point, but the Texans have only allowed one 250-yard passer — Buffalo's Josh Allen, who is much better than Brissett.

The Cardinals' offense will struggle mightily against Houston's defense.

BET TEXANS -9.5 (-115).

Over/Under

Arizona will struggle to score. If they score 2 touchdowns, it will be a shock. The question is whether the Texans can score enough for the Over to cash. They have only 1 game in their last 8 scoring over 30 points and have averaged 19.8 points in their last 4 games.

BET UNDER 42.5 (-110).

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This article originally appeared on Sportsbook Wire: Arizona Cardinals at Houston Texans odds, picks and predictions

Reporting by Jess Root, Sportsbook Wire / Sportsbook Wire

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