A number of factors go into building a winning 2025 Fantasy football strategy. Injuries are nearly always the main reason a season can be derailed. One can look no further than last year when San Francisco running back Christian McCaffrey missed all but four games. He was coming off a monster year in 2023, which saw him pile up 1,459 yards rushing and 14 touchdowns. In 2024, however, he ended up rushing for just 202 yards and zero touchdowns.

Despite all of the injury pitfalls, there are ways to avoid potential disaster by knowing how to balance risk and reward. One such way is with the help of SportsLine's Fantasy football cheat sheets and rankings. Who are this year's players you need to avoid, and what minor injuries may turn out to be disastrous to your Fantasy football team? Before f

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