The fourth-ranked Oregon Ducks will look to open their Big Ten season on a high note when they face the Northwestern Wildcats on Saturday. Oregon is coming off a 69-3 pasting of Oklahoma State, while Northwestern cruised to a 42-7 win over Western Illinois in Week 2. The Ducks (2-0), who won the Big Ten regular-season title at 9-0 last year and finished 13-1, were 5-0 on the road in 2024. The Wildcats (1-1), who placed 16th in the conference at 2-7 and 4-8 overall, were 2-4 on their home field.

Kickoff from Martin Stadium in Evanston, Ill., is at noon ET. Northwestern won the only previous meeting with Oregon, earning a 14-10 win in 1974. The Ducks are 27.5-point favorites in the latest Oregon vs. Northwestern odds, while the over/under for total points scored is 50.5 via SportsLine c

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