Key takeaways:

Production of Dengvaxia, the only dengue vaccine approved in the U.S., has been discontinued.

Another shot is available outside the U.S., and two other candidates have undergone late-stage trials.

The only dengue vaccine ever approved in the United States is being discontinued, raising questions about control of the mosquito-borne virus amid a decades-long surge in cases.

The vaccine, Dengvaxia, was approved by the FDA in 2019 for children aged 9 to 16 years living in U.S. territories where dengue is endemic, including American Samoa, Guam, Puerto Rico and the U.S. Virgin Islands.

The only dengue vaccine ever approved in the U.S. has been discontinued. Image: Adobe Stock

Despite dengue’s proliferation globally — WHO estimates that half of the world’s population is a

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