SANTA CLARA, Calif. — Arizona Cardinals running back James Conner was taken off the field on a cart with a right ankle injury in the third quarter of their loss to the San Francisco 49ers on Sunday.

Conner's leg buckled underneath him as he was tackled on a short run and members of the Cardinals' training staff immediately ran onto the field.

Several Arizona players came off the bench as both teams gathered around Conner as he was being treated. He was then taken off the field on a cart and was immediately ruled out for the rest of the game.

Coach Jonathan Gannon had no update on the extent of the injury following the loss, but his teammates were very concerned.

“It’s unfortunate,” quarterback Kyler Murray said. “Not only is he my teammate, I feel like that’s my brother. Seeing him g

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