Iowa State football lost its second-straight game, falling to the Colorado Buffaloes on the road in a 24-17 contest on Oct. 11.

The No. 21 Cyclones (5-2, 2-2 Big 12 Conference) lost a back-and-forth battle to Colorado (3-4, 1-3). It was the Buffaloes' first conference win of the season and their first win over a ranked opponent since coach Deion Sanders' debut victory over TCU on Sept. 2, 2023.

Iowa State seemed to lose momentum after a flag was thrown in the end zone for an apparent defensive pass interference was picked up, and the Cyclones had the ball picked off on the same play.

Abu Sama III finished with 177 yards and two touchdowns on 24 carries. Ben Brahmer led all Cyclone receivers with 56 yards on five catches. Quarterback Rocco Becht completed 18-of-33 passes for 205 yards

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