NFL picks against the spread for Week 7 from our expert staff

Week 6 of the 2025 NFL season is now behind us, and we have another full slate of games on the docket in Week 7.

A couple of prime-time games headline the slate with the San Francisco 49ers looking to bounce back from a loss to the Buccaneers in Sunday Night Football against a hot Atlanta Falcons team that has won its last two. Then, in the first of two Monday Night Football games, that Bucs team hits the road to take on the Detroit Lions, who are also looking to get back on track after a prime-time loss to the Kansas City Chiefs.

That just scratches the surface of the Week 7 slate. Here are the picks against the spread from our expert staff.

Name	Week 6 Record	2025 Record
Prince Grimes	6-9	41-49-3
Charles Curtis	7-8-1	41-49-3
Cory Woodroof	N/A	36-39-3
Robert Zeglinski	7-8	46-44-3
Christian D'Andrea	8-7	43-47-3
Tyler Nettuno	5-10	44-46-3

Pittsburgh Steelers at Cincinnati Bengals (Thursday Night Football)

Opening Line: Bengals -4.5

Grimes: Bengals +5.5

There's a reason Mike Tomlin is mad about the Joe Flacco trade. I bet we find out Thursday night.

Curtis: Bengals +5.5

Weird stuff happens in short weeks and the Bengals' offense does just enough to cover.

Zeglinski: Steelers -5.5

Pittsburgh doesn't have too many "gimme" games on its schedule. This one against washed-up old nemesis Joe Flacco qualifies, though.

D'Andrea: Steelers -5.5

Mike Tomlin is salty and Aaron Rodgers is finding his rhythm. Now he gets to face the league's 27th-ranked passing defense.

Nettuno: Steelers -5.5

Do I believe in Joe Flacco in Cincinnati? No, I do not.

Los Angeles Rams vs. Jacksonville Jaguars (Sunday morning, in London)

Opening Line: Rams -3.5

Grimes: Rams -3

If the Rams play well enough to win, I think they get it done by at least a touchdown.

Curtis: Rams -3.

Weird stuff ALSO happens in London, but I'll take the better team.

Zeglinski: Rams -3

It doesn't feel like the Rams have played a complete game yet. They're way overdue to do so against good competition.

D'Andrea: Jaguars +3

Jacksonville has won three of its last four in London and those were some... grim Jags teams. The Rams may be the best competition they've faced over there since 2019, but this also may be the best Jacksonville team we've seen since the salad days of Blake Bortles.

Nettuno: Jaguars +3

I don't feel good about this at all, but the Jags play well in London historically. They're banged-up but I think they'll bounce back here.

Las Vegas Raiders at Kansas City Chiefs

Opening Line: Chiefs -9.5

Grimes: Chiefs -12

The Chiefs are at home, and they might be finding a rhythm.

Curtis: Chiefs -12

Rashee Rice will be back and the Chiefs will pile up the points.

Zeglinski: Chiefs -12

The Chiefs have their confidence and Rashee Rice, who is returning from suspension for a felony related to reckless, dangerous driving, back? Godspeed, Raiders.

D'Andrea: Raiders +12

That's just too many points in a divisional rivalry where the Raiders typically rise up for a trip to Missourah.

Nettuno: Chiefs -12

Kansas City really seems to be starting to hit its stride.

Miami Dolphins at Cleveland Browns

Opening Line: Dolphins -1.5

Grimes: Dolphins +2.5:

I picked the Browns to win outright, but I can't in good conscious lay points with that team.

Curtis: Browns -2.5

I can't believe I'm betting on a rookie QB, but I'm really betting on the Browns' defense and Tua Tagovailoa struggling.

Zeglinski: Browns -2.5

Tua Tagovailoa, a supposed leader, called out the Dolphins for their ... leadership. We're either about to see an incredible response or a beautiful meltdown. There's no in between.

D'Andrea: Browns -2.5

The Mike McDaniel era was fun. It probably doesn't survive this.

Nettuno: Dolphins +2.5

These teams both stink. I guess I'll take the one that has been a bit more competitive.

New Orleans Saints at Chicago Bears

Opening Line: Bears -7.5

Grimes: Bears -5

It took a little luck, but Chicago's confidence should be growing with last week's win.

Curtis: Bears -5

I like what I saw last week.

Zeglinski: Bears -5

After two straight gritty culture wins, Ben Johnson's Bears are due for a comfortable double-digit victory over inferior competition.

D'Andrea: Bears -5

New Orleans has more chops than we expected, but the Bears end their string of nailbiters here.

Nettuno: Bears -5

I still don't totally trust Chicago, but it should be fine here.

Philadelphia Eagles at Minnesota Vikings

Opening Line: Eagles -3

Grimes: Vikings +1.5

Carson Wentz revenge game?

Curtis: Vikings +1.5

Minnesota's coming off the bye and something is clearly wrong in Philly just months after winning a Super Bowl. What a hangover.

Zeglinski: Eagles -1.5

Carson Wentz, J.J. McCarthy, it don't matter. The Eagles are pissed and no one should want to play them in this state.

D'Andrea: Eagles -1.5

The Philly defense is a concern. If it gets carved up by Carson Wentz or JJ McCarthy, that modest head-tilt in the Eagles' direction becomes some full-on bug-eyes and head-shaking.

Nettuno: Eagles -1.5

It would be so funny if Carson Wentz beat Philly, but it's not gonna happen.

Carolina Panthers at New York Jets

Opening Line: Jets -1.5

Grimes: Panthers -1.5

The Panthers are... better than the Jets.

Curtis: Panthers -1.5

I really want to give the Jets the benefit of the doubt at home and desperately needing a win. But then they'll give up 300 yards on the ground to Rico Dowdle and Chuba Hubbard.

Zeglinski: Panthers -1.5

It took six whole weeks for Jets players to give up on Aaron Glenn. The Panthers are still playing for Dave Canales. There's the difference in this game.

D'Andrea: Jets +1.5

New York's gotta win sometime, and Justin Fields goes from the league's toughest pass rush to its worst. And you can get the over/under at 41.5, you say?

Nettuno: Jets +1.5

The Panthers are better than the Jets, but if New York doesn't get its first win here, I don't know when it's going to happen.

New England Patriots at Tennessee Titans

Opening Line: Patriots -1.5

Grimes: Patriots -7

Mike Vrabel revenge game.

Curtis: Patriots -7

The Pats are good. The Titans are not (for now).

Zeglinski: Patriots -7

Jeffery Simmons against the New England OL is scary but the Patriots are a better team which, you know, didn't just fire its underwhelming coach.

D'Andrea: Patriots -7

Mike Vrabel is gonna return home, remember how he was shown the door thanks in large part to a front office that couldn't maximize its resources, and then smush the Titans.

Nettuno: Patriots -7

I don't believe a red-hot New England team will struggle in the Mike Vrabel revenge game against a Titans team that has already fired his replacement.

Indianapolis Colts at Los Angeles Chargers

Opening Line: Chargers -6

Grimes: Colts +1.5

The Chargers are kinda mid right now with all the injuries.

Curtis: Chargers -1.5

Mannnn I dunno. I'm taking the home team that doesn't even have the best home environment! What am I doing here?

Zeglinski: Chargers -1.5

I still don't trust the Daniel Jones Colts. Which is funny to say in a game against the CHARGERS of all teams but here we are. I never said my logic is logical.

D'Andrea: Colts +1.5

Feels like a coin flip, take the points.

Nettuno: Colts +1.5

Why, exactly, do the Chargers deserve to be the favorite here?

New York Giants at Denver Broncos

Opening Line: Broncos -7.5

Grimes: Giants +7

New York's defense could give Bo Nix some trouble out there (fingers crossed).

Curtis: Giants +7

This should be more like -5.5 given Jaxson Dart's magic.

Zeglinski: Broncos -7

Jaxson Dart showed real promise last Thursday night but Denver is a different story. The Broncos' monstrous defense should squash him like a bug.

D'Andrea: Broncos -7

Oh the Denver defense is gonna have Jaxson dart in HELL.

Nettuno: Giants +7

Denver's defense should allow it to win, but I don't think it will score enough to pull away.

Green Bay Packers at Arizona Cardinals

Opening Line: Packers -2.5

Grimes: Packers -6.5

The Cards are freefalling after four straight losses.

Curtis: Packers -6.5

The Cards are bad!

Zeglinski: Packers -6.5

I'm still not sure if the Packers are "good" under traditional parameters but I feel pretty confident about them being at least a touchdown better than Arizona.

D'Andrea: Cardinals +6.5

Green Bay has too much of a history letting flawed teams stick around, especially on the road.

Nettuno: Packers -6.5

Green Bay should be fine against a bad team.

Washington Commanders at Dallas Cowboys

Opening Line: Commanders -3

Grimes: Commanders -1.5

The Cowboys couldn't spell D right now, let alone play it.

Curtis: Cowboys +1.5

Dak Prescott, MVP?!

Zeglinski: Cowboys +1.5

Dallas sneakily has the NFL's No. 1 offense this season. (Don't ask about the defense.) That's enough to bet on a shootout against Jayden Daniels where the team with the ball last wins.

D'Andrea: Cowboys +1.5

Another coin toss. Take the points (especially with the home team getting them in a rivalry game).

Nettuno: Commanders -1.5

Washington hasn't been great, but the Cowboys defense stinks.

Atlanta Falcons at San Francisco 49ers (Sunday Night Football)

Opening Line: 49ers -6.5

Grimes: Falcons +2

Gotta pick up the points with a hot Falcons team.

Curtis: Falcons +2

I know they're traveling West but that was VERY impressive last week. And their defense is legit.

Zeglinski: Falcons +2

Overcoming the loss of Nick Bosa AND Fred Warner is a lot to ask against Bijan Robinson.

D'Andrea: Falcons +2

The Niners are so woefully cursed by injury that I can't even back them against a Falcons team whose last road trip ended in a 30-0 loss to the PANTHERS.

Nettuno: Falcons +2

I don't know if Atlanta can keep it up, but the injuries are starting to pile up in San Francisco.

Tampa Bay Buccaneers at Detroit Lions (Monday Night Football)

Opening Line: Lions -3.5

Grimes: Bucs +5.5

The Bucs played a more dominant Lions team closer than this last season.

Curtis: Buccaneers +5.5

Baker Mayfield, NFL MVP?!

Zeglinski: Buccaneers +5.5

These two teams are, quite literally, exactly the same. Both are offensively-driven and both are led by former (and unfairly maligned) No. 1 picks. This should be a push.

D'Andrea: Bucs +5.5

If only because Tampa cannot play a normal game.

Nettuno: Bucs +5.5

This may just be the best team in the NFC, man.

Houston Texans at Seattle Seahawks (Monday Night Football)

Opening Line: Seahawks -1.5

Grimes: Texas +3

Give me the points in a potential defensive battle.

Curtis: Seahawks -3

I don't like either side of this, so I'll bet on Seattle fans to help out.

Zeglinski: Seahawks -3

The Texans can't block. That is, uh, a problem against a Mike Macdonald defense.