Two sets of division leaders clash to headline the NFL Week 10 schedule. On Sunday, the AFC East-leading New England Patriots, led by quarterback Drake Maye, battle the NFC South-leading Tampa Bay Buccaneers and quarterback Baker Mayfield. On 'Monday Night Football,' Jalen Hurts leads the Philadelphia Eagles into Lambeau Field to face Jordan Love and the Green Bay Packers. Both Tampa Bay and Green Bay enter as 2.5-point favorites. Another matchup involving contenders sees the Los Angeles Rams (6-2) traveling to San Francisco to face the 49ers (6-3) in a key NFC West matchup.

The Rams are 3.5-point favorites as Matthew Stafford looks to avenge a 26-23 overtime loss to San Francisco on Oct. 2. He has won three of his last four starts against the 49ers. The largest spread is Buffalo at Miami

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