All trains departing north from London Euston have been cancelled due to a significant fault in the signalling system. This disruption has left many passengers stranded, with reports of trains remaining stationary for over two hours. The issue originated in the Stafford area and has affected multiple routes operated by Avanti West Coast. Key destinations impacted include Manchester, Liverpool, Scotland, and North Wales. Avanti West Coast has communicated the situation via social media, stating, "Departures from London Euston are suspended due to a major fault with the signalling system in the Stafford area. This affects multiple Avanti West Coast routes, including journeys to/from Manchester, Liverpool, Scotland and North Wales. Please do not attempt to travel as major disruption is expected until the end of the day." Passengers are advised to avoid travel as delays and cancellations are anticipated to continue throughout the evening. The situation remains fluid, and further updates are expected as the railway company works to resolve the signalling issues.