If you were around during the late '80s to mid-'90s, you likely remember funnyman Dave Coulier's turn as Uncle Joey, the lovable live-in uncle in ABC's popular sitcom "Full House." However, these days the comic is going through something deadly serious: a second bout of cancer.

In October 2025, the 66-year-old actor revealed to Today that he has tongue cancer. "A couple of months ago, I had a PET scan, and something flared on the scan," Coulier told the show via a phone interview. "The doctor said, 'We don't know what it is, but there's something at the base of your tongue.'" And, while the initial biopsy didn't show any signs of cancer, a second, larger biopsy was positive, leading doctors to diagnose him with early-stage, P16-positive oropharyngeal squamous cell carcinoma.

However, t

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