Julian Sayin #10 of the Ohio State Buckeyes throws a pass against the Michigan Wolverines during the second quarter at Michigan Stadium on November 29, 2025 in Ann Arbor, Michigan. Getty Images Gambling content 21+. The New York Post may receive an affiliate commission if you sign up through our links. Read our editorial standards for more information.

College Football Playoff seeding, a Heisman Trophy and a Big Ten title.

The stakes are as high as a college football game can offer between No. 1 Ohio State and No. 2 Indiana on Saturday night.

There are zero losses between these two teams, but a 4.5-point spread favoring the Buckeyes.

Ohio State’s regular season was as close to flawless as one could script. It’s a resume that needs no introduction, but Indiana is looking at the N

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