The Colts have activated second-year linebacker Jaylon Carlies off IR ahead of Sunday's road game in Jacksonville, the team announced Saturday, paving the way for linebacker to potentially make his 2025 season debut in a pivotal late-season divisional matchup.

Defensive end Tyquan Lewis has been downgraded to out. Kicker Blake Grupe and defensive tackle Chris Wormley have been elevated from the practice squad.

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