The Week 1 NFL schedule kicks off in just two days, and there are some tight Week 1 NFL odds to deal with as there are nearly a dozen NFL games with a line of a field goal or less. Some of these NFL odds include Chiefs vs. Chargers (+3), Buccaneers vs. Falcons (+2.5), Dolphins vs. Colts (-1) and Steelers vs. Jets (+2.5). There are just two contests with Week 1 NFL spreads of over a touchdown, including when Cam Ward makes his pro debut as his Titans are 8-point underdogs to the Broncos, making them the second biggest underdogs of the week behind the Cowboys (+8.5) to the Eagles.

Whatever NFL betting trends you decide to follow for the opening slate of games, you certainly want your football bets to kick off the 2025 NFL season to start off on the right note. All of the updated Week 1 NFL

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