The San Francisco 49ers went into Sunday's game against the Seattle Seahawks already shorthanded, and they added three more players to the injury list before their Week 2 contest against the New Orleans Saints .

Per Ian Rapoport of NFL Network, the status of quarterback Brock Purdy is unknown after he suffered shoulder and toe injuries. Tight end George Kittle will miss multiple weeks due to a hamstring injury and WR Jauan Jennings needs a CT scan on his shoulder.

In addition: TE George Kittle is out multiple weeks with a hamstring injury, while the team is doing a CT scan on Jauan Jennings to make sure his shoulder is OK. https://t.co/1VOBSmMyOL — Ian Rapoport (@RapSheet) September 8, 2025

The 49ers believe Kittle will miss three to five weeks, which is a significant amoun

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