The San Francisco 49ers may have to make do without three more offensive starters in Week 3.

Head coach Kyle Shanahan on Monday spoke with reporters on a conference call and started with updates on players injured in Sunday’s win over the New Orleans Saints.

“Injuries from the game. (FB Kyle Juszczyk) Juice will be in the protocol this week,” Shanahan said. “Ben Bartch had a high ankle sprain, he will be out for a while. Siran Neal will also be in the concussion protocol, reported some symptoms today. Spencer Burford hurt his knee. We’ll have to evaluate him throughout this week. Jauan Jennings hurt his ankle. We’ll have to evaluate him throughout this week.”

Bartch went down early in Sunday’s game and never returned. Rookie seventh-round pick Connor Colby filled in for him and figures

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