Michigan State football is playing some Saturday night (and early Sunday morning) football, with a trip out to the West Coast for its first Big Ten matchup of the 2025 season.

The Spartans (3-0) face USC (3-0) on Saturday, Sept. 20, at the Los Angeles Memorial Coliseum in Los Angeles. The game will be broadcast on Fox with kickoff at 11 p.m. ET.

The Spartans are unbeaten after a 41-24 win against FCS opponent Youngstown State on Sept. 13, but enter the USC game as a heavy underdog, with the Trojans favored by 19½ points as of Saturday evening. THE PICKS: Who wins in Week 4, Spartans or Trojans?

However, Michigan State did get some positive news on Friday when wide receiver Nick Marsh and running back Makhi Frazier, both of whom left the Youngstown State game with injuries, were c

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